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I’m a pharmacist from a hospital in China, and using NONMEM is a big part of my research routine. I think PUMAS is one of the coolest tools I’ve seen because it brings GPU capabilities into play. I’d love to share this with my colleagues, and I’ve already started doing that!
For example, the Generation of Virtual Populations for Quantitative Systems Pharmacology is really interesting. This method lets us combine population structure with individual information in a smart way, which I find super intriguing.
There’s definitely more creative work we can explore. QSP, for instance, aims to get to the first principles, which is great for engineers and scientists who prefer a solid foundation rather than just statistics. But I think QSP might need a bit more knowledge about kinetics or some background info, which can be quite challenging.
That’s what I’ve got for now, and I’d love to hear any more thoughts you have! Thanks!