# Pumas version 0.12.0 (Alpha 12) released

**URL:** <https://discourse.pumas.ai/t/pumas-version-0-12-0-alpha-12-released/343>\
**Category:** Announcements\
**Created:** [May 14, 2020, 8:14am UTC](https://discourse.pumas.ai/t/pumas-version-0-12-0-alpha-12-released/343 "2020-05-14T08:14:24Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![andreasnoack](https://yyz2.discourse-cdn.com/flex030/user_avatar/discourse.pumas.ai/andreasnoack/32/22_2.png) [@andreasnoack](https://discourse.pumas.ai/u/andreasnoack)\
**Post date:** [May 14, 2020, 8:14am UTC](https://discourse.pumas.ai/t/pumas-version-0-12-0-alpha-12-released/343/1 "2020-05-14T08:14:25Z")

</div>

A new release of Pumas is now available in the JuliaProRegistry. You can upgrade your current installation of Pumas by simply running `] up Pumas` at the command prompt in JuliaPro.

# Release Notes for Pumas v0.12.0

## Features

- Sundials.jl is now supported when using steady-state dosing.
- Information criteria functions `aic` and `bic`, as well as the shrinkage and `npde` functions, now have methods for `FittedPumasModel`.
- The `predict` method now works for models fitted with `NaivePooled`.
- Estimation of models with dose control parameters is now supported both for closed-form and ODE based models.
- New `concthreshold` parameter in `NCA.lambdaz` to filter out tiny concentrations.
- Support for passing `obstimes` in `predict` methods.
- Many new docstrings.

## Deprecations

- `PKPDAnalyticalProblem` has been renamed to `AnalyticalPKPDProblem`.
- `ZeroSpline` from `DataInterpolations` has been renamed to `ConstantInterpolation`.

## Bugfixes

- Doses in NCA that are outside of observed time are now automatically removed.
- Optional arguments used during the model fitting is now correctly pased to diagnostics functions. This ensures that e.g. ODE solver tolerances are identical between model fitting and diagnostics computations.
- It is now possible to use random effects in the `@vars` block. That means that random effects can be applied to the solution of the dynamical system instead of just to the parameters of the dynamical system.
- Bugfix for offset handling in `DosageRegimen`.
- Fix printing of coefficient tables when the calculation of the covariance matrix has failed.
- Fix printing of the number of successful bootstrap samples.

## Compatibility

- Pumas now supports Julia 1.4. Julia version 1.4.1 includes important compilation time fixes for Pumas relative to version 1.4.0.
- StatsBase 0.33 is now supported.
- RecipesBase 1.0 is now supported.
- AdvancedHMC 0.2.12 is now required.
- DataInterpolations 2.0 is now required.
- StatsFuns 0.9 is now supported.